Eleven previous births have used a transplanted uterus but from a living donor, usually a relative or friend.
Uterus transplantation was pioneered by Swedish doctor Mats Brannstrom, that has delivered eight children from women who got wombs from family members or friends. Two babies are born at Baylor University Medical Center at Texas and one in Serbia, also by transplants from living donors.
At 2016, doctors at the Cleveland Clinic transplanted a uterus from a deceased donor, however, it collapsed after an illness developed.
The Cleveland program is continuing to use deceased donors. Falcone said the simple fact that the transplant was successful after the uterus has been preserved in ice for nearly eight hours demonstrated how resilient the uterus is. Doctors try to keep the time that an organ is with blood flow to a minimum.
Brazilian doctors are reporting the world’s first baby born to a woman with a uterus transplanted from a deceased donor.The baby girl was sent last December by a woman born without a uterus due to a rare syndrome.
“There are still a lot of things that we don’t understand about pregnancies, such as how embryos implant,” said Dr. Cesar Diaz, who co-authored an accompanying commentary in the journal. “These transplants will help us comprehend implantation and each stage of pregnancy.”
Other experts said the understanding gained from such procedures might also fix some lingering mysteries about pregnancies.
The girl became pregnant through in vitro fertilization seven months after the transplant. The donor was a 45-year-old woman who had three kids and died of a stroke.
“The Brazilian team has shown that using dead donors is a feasible option,” said the clinic’s Dr. Tommaso Falcone, who was involved in the Ohio case. “It could give us a bigger source of organs than we believed were possible.”
Two more transplants are intended as part of the Brazilian study.
The receiver, who was not recognized, gave birth by cesarean section. Doctors also removed the uterus, partially so the girl would no more have to take anti-rejection drugs. Almost a year after, mother and baby are both healthy.